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[German version] (σφυγμός/ sphygmós, Latin pulsus). Although a pounding pulse was long recognized as an indication of illness, it seems to have been Aristotle [6] (Hist. an. 521a; De respiratione 479b) who was the first to connect the phenomenon with the heart [1]. His assertion that the pulse was a normal, constant presence in all blood vessels was disproved by Praxagoras, who was able to show that only arteries had a pulse. His view that arteries contained only pneûma and functioned independent of the heart was in turn questioned by his pupil Herophil…

[German version] of Sardis. Teacher and physician, who worked around AD 390. The son of a physician and a pupil of Zeno of Cyprus, he was well respected, particularly regarding his services to practical therapy, pharmacology, the art of bandaging, and surgery. In addition, he was a philosopher with particular gifts in medical prognostication as well as in fortunetelling (Eunapius, Vitae Philosophorum 499). Furthermore, he is reported to have distinguished himself as a well-known orator and poet, even though none of his works have survived. Nutton, Vivian (London)

[German version] (Ἄκρων; Ákrōn) [of Acragas] Son of a doctor of the same name (Diog. Laert. 8,65), older contemporary of Hippocrates. He was supposed to have rid Athens of the pest by lighting big fires in 430 BC (Plut. De Is. et Os. 80 [cf. 1]). The  Empiricists (Ps.-Gal. 14,638) considered A. as founder of their school and as such he entered the doxographic tradition [2]. It is possible that he participated in the debates regarding the epistemological value of sensory perception (he was familiar …

[German version] Medical writer, 4th cent. AD, author of a Latin paraphrase of a Greek letter to (an undefined) king Antigonus that is passed down under the name of Hippocrates [6] and that contained a dietetic plan and advice on treating diseases of the head, chest, belly and kidneys. This paraphrase is extant in the introduction to a medical treatise of Marcellus Empiricus, where it is preceded by a letter of L. to his sons. Both texts probably belonged to the introduction to a medical work by L. that is lost today. Nutton, Vivian (London)

[German version] In Babylonian, Egyptian and also Greek medicine, blood-letting was part of standard medical practice. This procedure was carried out either by directly opening a vein, by scarification or by using a cupping vessel. Considering how often the latter are depicted on monuments connected with physicians, cupping may have been the most common method [1]. Two notions seem to have favoured phlebotomy: on the one hand, it supposedly prevented the stagnating of the blood and its transformat…

[German version] (ἀλεξιφάρμακα; alexiphármaka). ‘Medications that protect from poisons’. The search for effective antidotes is as old as the poisons themselves.  Theophrastus ( c. 380-288/5 BC) already presented discussions of a few antidotes (fr. 360, 361 Fortenbaugh), but a more serious investigation into poisons seems to have begun in Alexandria with  Herophilus and  Erasistratus (around 280 BC) and was continued by Apollodorus and Nicander of Colophon (2nd cent. BC), whose Theriaka and Alexipharmaka are the oldest surviving treatises on the topic. Alexipharmaka can be us…

[German version] I. Greece Greek medicine is fundamentally different from Egyptian and Babylonian medicine because it allots dietetics in the broader sense of a regime of eating, drinking, exercise and bathing, a key role within therapeutics [2. 395-402; 3]. Originally, dietetics referred to the administering of balanced foods in liquid, pasty or solid form, depending on the degree of illness (Hippocr. De medicina vetere 5 [4. 241-257]). However, about the mid 5th cent. BC it expanded well beyond a …

[German version] (Ἀρεταῖος; Aretaîos) of Cappadocia. Greek Hippocratic physician who was influenced by Pneumatic theory. [13] therefore assigned him to the middle of the 1st cent. AD. A.'s name was first mentioned in the late 2nd. cent as the author of a text about prophylactics in Ps.-Alex. Aphr. De febribus 1, 92, 97, 105. However, Galen repeats A.'s story of a leper that appeared in Morb. chron. 4,13,20 without any reference to the source in Subfig. emp. 10 = Deichgräber 75-9. Thirty years later…

[German version] A. Near Eastern Mental illnesses (MI) are described in both Jewish and Babylonian texts. Sometimes physical signs are indicated, as in epilepsy, sometimes behaviours are described as in 1 Sam 16:14-16; 21:13-15, but all MI are ascribed to the intervention of God, or, in texts from 500 BC onwards, of a variety of demons [1]. Treatment might be limited to confinement (Jer 29:26-8) or exorcism, including music, but the Jewish ‘Therapeutae’ took an approach that involved the entire lifes…

[German version] (Μνησίθεος; Mnēsítheos). Athenian doctor, fl. 350 BC. His tomb was seen by Paus. (1,37,4). He was wealthy enough to erect statues and was one of the dedicators of the beautiful ex-voto inscription to Asclepius IG II2 1449. He is frequently associated with Dieuches [1]; he wrote extensively about dietetics including diets for children, and is counted amongst the more important Dogmatic physicians (Dogmatists) [1]. Galen ascribes to him a logical classification of illnesses that follows Plato's method (fr. 10,11 Bert…

[German version] Greek grammarian, middle or end of the 1st cent. AD, author of a glossary of Hippocratic words, which he dedicated to  Andromachus [4 or 5], a doctor at the imperial court in Rome [2; 3]. The alphabetic structure of the glossary, in its surviving form, does not go back to E. since, in his preface (9), he expressly emphasizes that he had explained the words in the sequence of their appearance in c. 37 Hippocratic texts which in turn could be classified into 1) semiotic, 2) physiological-aetiological, 3) therapeutic texts, 4) miscellaneous, 5) texts on…

[German version] A. Egyptian The high prestige widely accorded to Egyptian medical practitioners for their surgical skills (Hdt. 3,129), was well-earned. Skeletal finds show the successful treatment of bone fractures, esp. in the arms, and rare cases of trepanation. However, there is no reliable indication of surgical intervention in body cavities [1; 2]. The great diversity of knives, spoons, saws and needles reflects a highly-developed specialism, rooted in wide-ranging medical practice. Early pap…

[German version] Masseur, a profession that seems to have become fashionable in the 1st cent. AD (e.g. CIL 6,9476) but the linking of medicine and gymnastics extends as far back as Herodicus [1] of Selymbria (5th cent. BC). Trimalchio was treated by three aliptae (Petron. Sat. 28). Pliny considers this entire branch of medicine a form of quackery (HN 29,4-5). Vespasian however guaranteed all who practiced this art various privileges (FIRA 1,77) and Pliny the Younger managed to persuade Trajan to confer Roman (and Alexandrian) citizenship to his Egyptian iatraleiptes Harpocrates, w…

[German version] (μέλαινα χολή/ mélaina cholḗ, ‘black bile’). The fourth humour in the tradition of Hippocratic medicine represented by De natura hominis, ch. 4, and later by Rufus of Ephesus and Galen. It was predominant in autumn, associated with the element earth, and cold and dry. It was viewed as the antithesis of blood, having many deadly properties [1]. According to Galen (De atra bile 5,104-148 K.) in its purest form it was highly destructive to everything it touched, and had its origin in the spleen. Not ev…

[German version] Greek physician, mid 5th cent. BC. The story recounted in Sor. Vita Hipp. 5, that E. cured Perdiccas II of Macedonia of an illness caused by unrequited love, arose comparatively late and is rather fantastical. According to Galen (17a,886), he provided the most important contributions to the so-called ‘Cnidian Sentences’, which have survived only in fragments [1. 65-66; 2. 14-26]. In the opinion of some ancient scholars some of his works, especially those dealing with dietetics, were taken up into the Hippocratic Corpus (Gal. 6,473; 7,960; 16,3). E. regarded disea…

[German version] Originally meaning a teacher of medicine (esp. in Alexandria), iatrosophistes could later refer to any experienced practitioner ( medicus sapientissimus, Corpus Glossatorum Latinorum 3,600,32 Goetz), either in orthodox medicine (e.g.  Agnellus, In Galeni De sectis commentarium 33) or in the magical arts of healing (Ps.-Callisthenes, Vita Alexandri 1,3) [1]. Contrary to the emendation by von Arnim in Dion. Chrys. 33,6, the term was probably not coined before the late 4th cent. AD (Epiphanius, Adversu…

[English version] Documentary evidence for a use of the HO in Late Antiquity is ambiguous. Gregory of Nazianzus (Greg. Naz. Or. 7,10) reported that his brother Caesarius did not have to swear the oath as a medical student in Alexandria, thus implying that others probably had to. However, there is no record for the Byzantine or Muslim world to confirm any official obligation to swear this oath, even though it was evidently well-known. In practice, it was superseded by the Galenic concept equating e…

[German version] (‘birth-helper’, ‘midwife’). Midwifery was usually practiced by women but was not exclusively in their hands. A Parian inscription, for example, records two male birth-helpers (IG 12,5,199) and the preserved treatises on midwifery address a male readership. Iatromaia as an occupational name appears in two Roman inscriptions of the 3rd and 4th cents. AD (CIL 6,9477f.); in one, a Valeria Verecunda is named as the ‘first iatromaia in her region’, an epithet that seems to refer to the quality of her work rather than a position in a collegium.  Midwife Nutton, Vivian (Lon…

[German version] A. History The Empiricists are a Greek school of physicians founded in about 250 BC by Philinus of Cos, a pupil of  Herophilus (Ps.-Galen Introductio; Gal. 14,683). According to Celsus (De med. pr. 10) it was founded somewhat later by Serapion of Alexandria. According to some doxographers the founder was Acron of Acragas (about 430 BC; fr. 5-7 Deichgräber). It is mentioned in the medical doxographies as one of the leading movements in Greek medicine even in the time of Isidorus of S…

[German version] (Φιλάγριος; Philágrios). Doctor from Epirus, fl. 3rd-4th cents. AD; he practised in Thessalonica and was the author of more than 70 books: treatises on dietetics, gout, dropsy and rabies as well as a commentary on Hippocrates [1]. He is often cited by later authors, especially in Arabic, for his treatment of diseases of the liver and spleen. Doctrinally, he often follows Galen, but pays particular attention to pneuma (Pneumatists) as the co-ordinating force in organisms. His name appears often in garbled form as Filaretus (e.g. frr. 131-133: Rhazes, Continens, V…

[German version] Physician and anatomist from Alexandria, active c. AD 152, the son of the anatomist and teacher  Numisianus. He compiled an extract of his father's works (Gal. De musculorum dissectione 18 B, 926, 935 K.), demonstrating his own considerable knowledge (Gal. Admin. anat. 16,1). He had a conversation with  Galen, when the latter arrived in Alexandria in c. AD 151, and Galen initially followed his anatomical lectures with benevolence (CMG V,9,1, p. 70). However, when Galen later requested to see the works by H.'s late father, their relatio…

[English version] Classical ideas of dietetics, based on the Hippocratic and Galenic notions of a balance between the four humours, continued to play an important role in medicine  into the 20th cent. (Humoral Theory). In Arabic medicine, all substances taken into the body had properties that could affect its health, for good or ill, and hence it was the doctor's duty to prescribe diets for health, as well as for disease, and equally that of his patient  to understand the rules for a healthy lifes…

[German version] I. Prehistory and early history Epidemic diseases (ED), or in the broadest sense, diseases that attack a large number of living beings simultaneously have been documented archaeologically since the middle of the Bronze Age, that is, since c. 2800 BC. Their appearance has been linked to population growth and the resulting ease with which disease can spread from animals to humans and from person to person [9. 251]. In Egypt, smallpox appears to have been known since c. 1250 BC, although papyri with medicinal content do not refer to this or any other compara…

[German version] (also Muscio) Translator and adapter into Latin of two gynaecological treatises by  Soranus of Ephesus.One of these, now lost in Greek, was a shorter manual of questions and answers; the second the celebrated Gynaikeîa (‘Gynaecology). Some MSS of M.'s compendium end with an appendix listing vaginal pessaries. Although not a faithful translation of Soranus, M.'s adaptation does offer help in the constitution of the Greek text, and it was the most popular treatise on gynaecology to survive from Antiquity into the …

[German version] (Ἀρχιγένης; Archigénēs) of Apamea. Physician, student of  Agathinus, lived under Trajan (AD 98-117) and died at the age of 63 (Suda s. v. Archigenes). He was an eclecticist and had close ties to the Hippocratic view that disease is caused by the dyscrasia of hot, cold, moist and dry. A. was predominantly influenced by the Pneumatists and wrote extensively about the study of the pulse. Galen (8,625-635) criticized his list of eight different pulse qualities as too tenuous. Some of t…

[German version] from Marseilles ( Massalia), physician, who came to Rome in the time of Nero (Plin. HN. 29,9). He gained renown when he combined astronomy with medicine by orienting the diet plans for his patients according to the course of the stars. When he died, he left 10 million sesterces after having already spent the same sum on repairing the walls and other defences in his native town. Nutton, Vivian (London)

[German version] (Οὐλιάδαι; Ouliádai). Family connected with medicine and healing cults in Velia [1] in southern Italy. The name derives from Oú lios (Οὔλιος;  Str. 14,1,6-8), one of the numerous epithets of Apollo (B. 4), and refers to his power both to harm and to heal (cf. Asclepius/Asclepiadae). The first verifiable member of this family was Parmenides. Statues and inscriptions in Velia, which were created primarily c. AD 20, represent members of the family, bearing the names Ulis or Uliades, as physicians and as φώλαρχοι/ phṓlarchoi; this probably suggests a cultic communit…

[German version] A., of Alexandria, worked during the first half of the second cent. as doctor and writer. He wrote about medicines and sympathetic remedies [1; 2]. The manuscripts also count among the writings of A. a treatise about toxicology [3], the core of which originated in A.'s time and which was apparently one of the main sources for  Aetius [3] of Amida, even if it shows signs of revisions in the meantime. Nutton, Vivian (London) Bibliography 1 E. Rohde, KS vol.1, 1901, 380-410 2 M. Wellmann, in: SBAW 1908, 772-777 3 S. Ihm, 1995.

[German version] The use of definitiones (‘discussions’) was extensive in medical teaching in the Greek as well as the Roman world (Gal. 1,306 K.; 19,346-7 K.). The most substantial surviving work of this genre is the Definitiones medicae ascribed to Galen (19,346-462 K.), the authenticity of which was doubted even in late antiquity (schol. in Orib. Syn, CMG 6,2,1, 250,29). Wellmann [1. 66] was of the opinion that their author lived towards the end of the 1st cent. AD, and was a member of the Pneumatic school. Although the work con…

[German version] (πυρετός/ pyretós, Lat. febris) strictly refers to a symptom only, i.e. a raise in body temperature, but all ancient medical authors frequently use this term to refer to a specific illness or class of illness. In modern diagnostic usage, the term covers a variety of conditions; thus the identification of any ancient ‘fever’ without any further sub-classification or other description of symptoms is bound to fail. Such aids to identification could consist of observations regarding the periodicity of fever attacks, as in the febris tertiana or febris quartana, when epi…

[German version] (φαλλός/ phallós, lat. mentula (for synonyms, see [1]). Its anatomy, including the glans, scrotum, and testicles, was established by 250 BC, but its physiology, especially its capacity as to achieve an erection, was harder to explain. Galen ( De usu partium 15,3) called it a 'nerve-like part', and in De motibus dubiis discussed the possible effects of imagination on the process. Although circumcision (Circumcisio) was seen as essentially Jewish, infibulation was widely practised. Medical and surgical texts offer a variety of treat…

[German version] The two Greek terms μήτρα/ mḗtra and ὑστέρα/ hystéra are both of disputed etymology (Soran. Gynaecia 1,6) and are often used in the plural (the belief in its many chambers derives from animal anatomy). Hippocratic authors ( Corpus Hippocraticum ) shared the idea of the uterus as a jar moving up and down a tube in the body ( Vulva ) and closing in on itself during pregnancy. They were of the view that the uterus can, like a living creature, be attracted or repelled by pleasant or unpleasant smells, and that it held no fix…

[German version] From 1050 BC onwards we find careful descriptions of epilepsy and its various manifestations in Babylonian texts [1]. There, epilepsy is linked to gods, spirits, or demons. The belief in a religious cause of epilepsy and the corresponding treatment of it through religious, magical, and folk-medicinal methods can be traced throughout all of antiquity and across cultural borders. In c. 400 BC, the Hippocratic author of De morbo sacro propagated a purely somatic interpretation of epilepsy , wherein he suspected that changes in the balance of bodily fluids we…

[German version] (Καλλιάναξ; Kalliánax). Doctor, adherent of  Herophilus [1] and member of his ‘house’, which possibly refers to the fact that he worked in the mid 3rd cent. BC [1].  Bacchius [1] in his memoir on the early followers of Herophilus (Galen in Hippocratis Epidemiarum 6 comment. 4,10 = CMG V 10,2,2,203), mentions that C. quoted Homer and the Greek tragic writers if his patients told him that they were afraid of dying. He gave them to understand by this that only the immortals could esca…

[German version] In Late Antiquity in Alexandria [1] writings by Galenus and to a lesser extent by Hippocrates [6] were assembled into a medical compendium. Known as the '16 Books of Galen', it covers the basic areas of medicine  (including anatomy, physiology and therapeutics). According to Arab sources [1], a number of teachers ( Iatrosophistḗs ) in Alexandria are supposed to have written a series of summaries or abridgements of the books contained in this compendium, which were then collected under the title SA and translated into Arabic and perhaps also into Hebrew [2]. In…

[German version] (IDélos 1525). C. lived in about 150-120 BC; administrative official, ‘relative of king Ptolemy’, exegete (i.e. head of the civil service in Alexandria), director of the museum and ἐπὶ τῶν ἰατρῶν, a title that is often understood to mean the person responsible for all Egyptian doctors, which in turn led to the conclusion that there was a state organization of doctors. Kudlien is of the opinion that the title refers to the person responsible for the person in charge of the ‘tax on …

[German version] (Ερυξίμαχος; Eryxímachos) Son of  Acumenus, Athenian doctor and Asclepiad, 5th cent. BC. As a friend of the sophist Hippias (Pl. Prt. 315A) and of Phaedrus (Pl. Phdr. 268A; Symp. 177A), he plays an important part in Plato's Symposium, in which he delivers a long speech in honour of Eros (185E-188E). His slightly pedantic manner earns him only the good-natured laughter of the invited guests but contemporary parallels to his linking of natural philosophy and medicine can be found in the Corpus Hippocraticum. Nutton, Vivian (London)

[German version] (Πραξαγόρας; Praxagóras) of Cos. Doctor, at the end of the 4th cent. BC, teacher of Herophilus [1], Phylotimus, Pleistonicus and Xenophon. His family claimed its descent from Asclepius; his grandfather who shared the same name and his father, Nicarchus, were likewise doctors. His family continued to be very prominent on Cos for generations [1]. A poem composed by Crinagoras still survives on a statue in his honour (Anth. Plan. 273). Amongst the works of this doctor are a treatise on therapy in at least 4 books, a work about diseases in at least 3 bo…

[German version] (Ἀκεσίδας; Akesídas). According to Paus. 5,14, A. was considered a hero in Olympia and was elsewhere known under the name Idas. His name offers the assumption that he was worshipped as a healing god, who possibly shared a healing cult, which was very common on the Peloponnese, with  Paeonius,  Iason and  Heracles. Nutton, Vivian (London)

[German version] (Φανοστράτη; Phanostrátē). Greek-Athenian midwife and doctor, depicted on Attic grave stelae from the end of the 4th cent. BC (IG II/III2 6873; Clairmont, 2. 890). The inclusion of the professional title midwife suggests a certain degree of specialisation in medicine and shows at the same time that women were able to work as doctors and earn a considerable income, as is suggested by the quality and individual designs of the stone mason’s craftsmanship. Nutton, Vivian (London)

[German version] (Ἀγαθῖνος; Agathînos) of Sparta (Ps.-Gal. 19,353). Greek doctor of the first cent., student of Athenaeus of Attaleia, teacher of Archigenes and the Pneumatist  Herodotus. Even though he was mostly counted among the Pneumatists, some believed that he had founded his own, the Episynthetic or Eclectic School. The handed-down fragments of his writings allow connections to the Empiricists and Methodists to be recognized. He wrote about medicines (a fragment about stinking hellebore is i…

[German version] The idea that physical health was connected with bodily fluids was widespread. Mucus is already mentioned in ancient Egyptian medicine, and also in Babylonian medicine particular attention was paid to the quantity and colour of bodily fluids. The Greeks regarded   ichṓr of the gods, blood (α(̃ιμα; haîma) in humans and sap (χυμός; chymós) in plants as the bearers of life. These fluids (χυμοί/ chymoí, Latin humores) could also become dangerous in excess. Two humours, phlegm (φλέγμα; phlégma) and bile (χόλος; chólos or χολή; cholḗ), are already represented as hazard…

Nutton, Vivian (London) [German version] A. Arabic Medical Historiography (CT) The historiography of ancient medicine goes back at least to Late Antiquity, when a 'History of the Physicians' is said to have been written by John Philoponus (6th cent.). Material from this work was drawn upon by Ishaq ibn Hunayn (d. 910/911), for his own 'History' ( Ta'rikh al-atibba), which is largely concerned with chronology [11]. Ishaq's example was followed by a variety of writers in Arabic, some, like the bookseller Ibn an-Nadim (fl. 987), producing largely lists of…

[German version] (Σάλπη/ Sálpē). Midwife of the Hellenistic era, whose medical and cosmetic recipes were quoted by Plinius [1] in his Historia naturalis (Plin. HN 28,38; 28,66; 28,82; 28,262; 32,135; 32,140). Athenaeus [3] (Ath. 322a) knows a S. as the author of παίγνια/ paígnia (‘light poems’), but it is problematic to consider the two identical [1]. Nutton, Vivian (London) Bibliography 1 D. Bain, Salpe's ΠΑΙΓΝΙΑ; Athenaeus 322a and Plin. H. N. 28,38, in: CQ 48, 1998, 262-268.

[German version] The papyrus inventory no. 137 of the British Library in London is the most important surviving medical papyrus. It was written towards the turn of the 1st to the 2nd cent. and is divided into three parts: columns 1-4,17 contain a list of definitions that concern the páthē of body and soul (cf. the discussion in Gal. Meth. med. 1); columns 4,21-20,50, present different views about the causes of diseases; columns 21,1-39,32 deal with physiology. The text as well as many internal characteristics indicate that these chapters, thou…

[German version] (Δημοκήδης; Dēmokḗdēs) of Croton. Greek physician, lived about 500 BC and according to Hdt. 3,125 was the best physician of his age. He was the son of Calliphon and practised in Croton before going to Aegina. After a year the town of Aegina employed him for one talent as the community's physician but a year later he moved to Athens for a higher salary and finally into the service of Polycrates of Samos who paid two talents. After Polycrates' assassination D. was taken as a slave to…

Nutton, Vivian (London) [German version] A. Origins (CT) By AD 500, Greek medicine had become largely Galenic Galenism. Alternative medical theories no longer flourished, and even pragmatists like Alexander of Tralles did not reject Galenic ideas entirely. In Alexandria, and elsewhere in the Byzantine world that followed Alexandrian traditions, e.g. Ravenna, there was a teaching syllabus of Galen, the so-called 16 books - Summaria Alexandrinorum, and of Hippocrates that was commented upon by lecturers who expected of their audience also a grasp of Aristoteli…

[German version] Greek doctor and philosopher, teacher of  Galen, lived about AD 150 in Asia Minor (Gal. 19,58, CMG V 10,2,2, 287). A long-standing student of  Quintus (Gal. 18A, 575) and follower of  Hippocrates, he interpreted at least some of their teachings in a Stoic sense, e.g., from the field of psychology, in which he followed the Stoic Simias (Gal. 19,58; 18b, 654]. The Hippocratic commentary, which is ascribed to him in the Galen edition by Kühn at Gal. 16,484, is a Renaissance forgery. Nutton, Vivian (London)

[German version] Latin contagio, ‘infection’, refers to the transmission of disease (TD) from person to person, directly or through an intermediary. TD is associated with the idea of pollution: Judaism, for instance, holds that people suffering from certain diseases (such as leprosy) or menstruating women must be avoided (Purification). The stated reasons were either hygienic or religious. Similar precepts are known from ancient Babylon and Greece as well. The observation that those in close contac…

[English version] In Late Antiquity, a hospital was a place within an environment of religious character, where one cared for people in need including old and sick ones. In the early MA, along the great routes of pilgrimage, chains of small inns developed. Many Benedictine monasteries had their own hospital wards, which may also have catered for the needs of a large part of the public. As of the 11th cent., hospitals were constructed in cities, again under the influence of eastern Mediterranean cu…